On-site Quality Control of Beer Quantification of Isohumulones and Reduced Isohumulones Using the Agilent 1220 Infinity Mobile LC Solution

نویسنده

  • Sonja Schneider
چکیده

This Application Note shows the analysis of isohumulones in different beer samples using the Agilent 1220 Infinity Mobile LC Solution. Direct injection of beer samples and isocratic elution mode enables the user to perform easy on-site measurements in a mobile laboratory without time-consuming sample preparation or method development. With this setup, nonreduced and reduced isohumulone standards were analyzed with high precision and linearity. Isohumulones were determined and quantified in 14 different beer samples. The International Bitterness Units (IBU) were calculated for the tested beer samples revealing significant differences from, for example, lager beer to pils. Reduced isohumulones could only be detected in one beer sample, an American lager beer. On-site Quality Control of Beer Quantification of Isohumulones and Reduced Isohumulones Using the Agilent 1220 Infinity Mobile LC Solution

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Analysis of Counterfeit Antidiabetic Drugs by UHPLC with the Agilent 1220 Infinity Mobile LC

Counterfeiting in the pharmaceutical industry has become a serious and underreported problem, particularly in developing countries. This Application Note shows the analysis of antidiabetic drugs of the sulfonylurea class using the Agilent 1220 Infinity Gradient LC system with diode array detector (DAD). Both HPLC and UHPLC methods revealed excellent precision, accuracy and linearity as well as ...

متن کامل

Isohumulones, the bitter component of beer, improve hyperglycemia and decrease body fat in Japanese subjects with prediabetes.

BACKGROUND & AIMS A recent study reported that isohumulones, the bitter component of beer, activate peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma in vitro and decrease plasma glucose and lipid levels in diabetic mice. This study was to investigate the efficacy and safety of isohumulones for subjects with prediabetes. METHODS Ninety-four subjects with prediabetes w...

متن کامل

Comparison of system suitability results according to USP method USP/NF 23 for the analysis of Paracetamol (Acetaminophen) and Aspirin in pain relievers

This analysis used the system suitability test, developed on an Agilent 1200 Series LC system to test whether the Agilent 1220 and Agilent 1260 Infinity LC systems fulfilled the acceptance criteria. The chromatographic conditions of the system suitability test transferred to the Agilent 1260 and Agilent 1220 Infinity LC systems without changes. The results obtained were compared for compliance ...

متن کامل

Dietary isohumulones, the bitter components of beer, raise plasma HDL-cholesterol levels and reduce liver cholesterol and triacylglycerol contents similar to PPARalpha activations in C57BL/6 mice.

The effects of dietary isohumulones, the main components accounting for the bitter taste of beer, on lipid metabolism were examined. Young female C57BL/6N mice were fed diets containing isomerized hop extract (IHE), which consists mainly of isohumulones. Administration of IHE with an atherogenic (high-fat and high-cholesterol) diet for 2 weeks resulted in a significant increase in plasma HDL-ch...

متن کامل

Cancer Chemopreventive Potential of Humulones and Isohumulones (Hops α- and Iso-α-acids): Induction of NAD(P)H:Quinone Reductase as a Novel Mechanism

Phytochemical analysis and chemopreventive testing of a special “α-/β-acid free” hops extract led to the identification of isohumulones (hops iso-α-acids) as potent inducers of NAD(P)H:quinone reductase (QR) activity. CD values (concentrations required to double the specific activity of QR in Hepa1c1c7 cell culture) were in the range of 1.3 to 10.2 μg/mL, with CD value of trans-isohumulone < ci...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016